CONNECT 4 <i>APOE</i> : A randomized study of phone versus videoconference delivery of <i>APOE</i> genotype disclosure in the Generation Study

Both telephone and videoconference are reasonable options for disclosure of APOE results in cognitively unimpaired individuals across all genotypes. While satisfaction was slightly higher with TD, small differences in numerical perceived risk by genotype and reductions in state anxiety among non-white participants, suggest potential small benefits to VD for some subgroups.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70858_100327
Primary Topic
BRCA gene mutations in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

CONNECT 4 APOE : A randomized study of phone versus videoconference delivery of APOE genotype disclosure in the Generation Study

Pierre N. Tariot, Cara Cacioppo, Carolyn Langlois, Jessica B. Langbaum et al.
Alzheimer s & Dementia
BRCA gene mutations in cancer
article

CONNECT 4 APOE : A randomized study of phone versus videoconference delivery of APOE genotype disclosure in the Generation Study

Pierre N. Tariot, Cara Cacioppo, Carolyn Langlois, Jessica B. Langbaum, Demetrios Ofidis, Scott Y. H. Kim, Michelle Weinberg, Laura Eppelmann, Brian L Egleston, Elisabeth Wood, J. Scott Roberts, Jason Karlawish, Angela R. Bradbury, Eric M. Reiman
article en

Abstract

Both telephone and videoconference are reasonable options for disclosure of APOE results in cognitively unimpaired individuals across all genotypes. While satisfaction was slightly higher with TD, small differences in numerical perceived risk by genotype and reductions in state anxiety among non-white participants, suggest potential small benefits to VD for some subgroups.

Alzheimer s & DementiaVol. 21(S4)
Fox Chase Cancer Center (US), National Institutes of Health (US), University of Michigan (US), Banner Alzheimer’s Institute, University of Pennsylvania (US)
Openalex Percentile: Top 25%
BRCA gene mutations in cancer
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CONNECT 4 <i>APOE</i> : A randomized study of phone versus videoconference delivery of <i>APOE</i> genotype disclosure in the Generation Study — Pierre N. Tariot, Cara Cacioppo, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS