Downregulation of Gastric Acid Secretion Pathways in Alzheimer's Disease: Implications for Autonomic Dysfunction and Gastrointestinal Symptoms

The downregulation of gastric acid secretion and associated autonomic pathways in Alzheimer's disease (AD) points to a wider autonomic dysfunction within AD. These findings underscore the potential role of impaired gastrointestinal and autonomic pathways in AD. Further research is needed, with a focus on early detection and the implementation of therapeutic strategies to manage GI symptoms.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_101331
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Downregulation of Gastric Acid Secretion Pathways in Alzheimer's Disease: Implications for Autonomic Dysfunction and Gastrointestinal Symptoms

Meher Garg, Inhan Lee
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Downregulation of Gastric Acid Secretion Pathways in Alzheimer's Disease: Implications for Autonomic Dysfunction and Gastrointestinal Symptoms

Meher Garg, Inhan Lee
article en

Abstract

The downregulation of gastric acid secretion and associated autonomic pathways in Alzheimer's disease (AD) points to a wider autonomic dysfunction within AD. These findings underscore the potential role of impaired gastrointestinal and autonomic pathways in AD. Further research is needed, with a focus on early detection and the implementation of therapeutic strategies to manage GI symptoms.

Alzheimer s & DementiaVol. 21(S2)
Southern Illinois University School of Medicine (US), Ann Arbor Center for Independent Living (US)
Openalex Percentile: Top 33%
Alzheimer's disease research and treatments
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Downregulation of Gastric Acid Secretion Pathways in Alzheimer's Disease: Implications for Autonomic Dysfunction and Gastrointestinal Symptoms — Meher Garg, Inhan Lee · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS