Hippocampus and Amygdala Volume and Morphology in Neurodegenerative Disorders with Co‐morbid Epilepsy
We identified hippocampal body and tail atrophy in AD+Epi and right hippocampal head, tail, and amygdalar atrophy in nonAD+Epi demonstrating that mesial temporal morphology may serve as a neuroimaging correlate for epilepsy in ADRD. These lateralized and region-specific patterns highlight the possible role of epilepsy in altering the trajectory of neurodegeneration in ADRD, which warrants further investigation.
Authors
- Ifrah Zawar (ORCID: https://orcid.org/0000-0002-6103-4250)
- Jaideep Kapur (ORCID: https://orcid.org/0000-0002-8608-1352)
- Mark S. Quigg
- Shen ZM Zhu
- Carol A Manning
- P Thomas ZM Fletchet
Institutions
- University of Virginia (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_097534
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00