Efficacy and safety of anti-VEGF monoclonal antibody 601 for macular oedema in retinal vein occlusion: two phase IIa randomised clinical trials
These trials demonstrate that 601 is as effective and safe as ranibizumab for improving vision and reducing CST in RVO-related macular oedema. Phase III trials are warranted.
Authors
- Jingxiang Zhong
- Fang Wang (ORCID: https://orcid.org/0000-0002-5971-2622)
- Suqin Yu
- H. Wang
- Mingwei Zhao (ORCID: https://orcid.org/0000-0003-1370-6275)
- Yanli Liu (ORCID: https://orcid.org/0000-0002-2505-5695)
- Mengqi Wu (ORCID: https://orcid.org/0000-0001-9403-1745)
- Quanhong Han (ORCID: https://orcid.org/0000-0003-3502-9607)
- Baihua Chen (ORCID: https://orcid.org/0000-0001-6367-9119)
- X. Y. Li (ORCID: https://orcid.org/0000-0001-8333-0635)
- Shuo Zhao (ORCID: https://orcid.org/0000-0002-2544-7277)
- Songtao Yuan
- Zhang Ming (ORCID: https://orcid.org/0009-0001-3500-6520)
- Qinghong Zhou
- Xiaohong Meng
- Hong Dai
- Zongming Song
- Haomin Huang
- Yuyu Xu
- Jin Yao
- Jing Lou
Institutions
- Southwest General Health Center (US)
- Central South University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Shanghai Eye Disease Prevention & Treatment Center (CN)
- Peking University People's Hospital (CN)
- Southwest Hospital (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Henan Provincial People's Hospital (CN)
- Tianjin Medical University Eye Hospital (CN)
- Shanghai Sunshine Rehabilitation Center (CN)
- Jiangsu Province Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Henan Provincial Eye Hospital (CN)
- Shanghai Clinical Research Center (CN)
- First Affiliated Hospital of Jinan University (CN)
- Hangzhou Medical College (CN)
- Tianjin Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- British Journal of Ophthalmology
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1136/bjo-2025-327845
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00