Synergistic Neurodegeneration in Alzheimer's Disease with Lewy Body Co‐Pathology: Insights from Deep Learning and CSF α‐Synuclein Seed Amplification Assays
These findings underscore α-synuclein's synergistic role in amplifying AD-related neurodegeneration, highlighting the importance of combined biomarker assays and targeted interventions for individuals harboring co-existing AD and LB pathology.
Authors
- Breton M. Asken
- Hojjatollah Sadeqi
- Mostafa Reisi Gahrooei (ORCID: https://orcid.org/0000-0002-7633-9575)
- Zohreh Morshedizad
- Melissa J. Armstrong
- Abbas Babajani‐Feremi
- Babak Ahmadi
Institutions
- University of Florida Health (US)
- University of Florida (US)
- Alzheimer’s Disease Neuroimaging Initiative (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101717
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00