Plasma Biomarkers in Diverse Populations
A p-tau217 cut-off of 0.55 pg/ml aligns well with positive Aβ PET scans, indicating underlying AD pathology, and provides an effective balance of sensitivity and specificity in a multicultural cohort. Additionally, cognitive challenge tests may enhance diagnostic accuracy, offering scalable potential for early AD detection in underserved populations.
Authors
- David Loewenstein (ORCID: https://orcid.org/0000-0001-6788-2798)
Institutions
- University of Miami (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_101158
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00