Novel vascular damage markers in SLE: insights from carotid colour Doppler ultrasound and aortic oscillometry in the LUPCARD cohort

In the first study of CV surrogate markers in SLE combining oscillometry and carotid CDUS/GSUS, patients showed increased carotid pulsatility and resistance compared with controls. Furthermore, several patient-related and disease-related factors were identified as angiopathy predictors. These results suggest that combined evaluation of CV surrogate markers may help detect subclinical organ damage and improve CV-risk classification in SLE.

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Publication Details

Journal
RMD Open
Published
2025-10-01
DOI
https://doi.org/10.1136/rmdopen-2025-006070
Primary Topic
Systemic Lupus Erythematosus Research
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article
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article

Novel vascular damage markers in SLE: insights from carotid colour Doppler ultrasound and aortic oscillometry in the LUPCARD cohort

Andreas Schwarting, K. Triantafyllias, George Bertsias, Felix Tietze et al.
RMD Open
Systemic Lupus Erythematosus Research
article

Novel vascular damage markers in SLE: insights from carotid colour Doppler ultrasound and aortic oscillometry in the LUPCARD cohort

Andreas Schwarting, K. Triantafyllias, George Bertsias, Felix Tietze, Jacques-Eric Gottenberg
article en

Abstract

In the first study of CV surrogate markers in SLE combining oscillometry and carotid CDUS/GSUS, patients showed increased carotid pulsatility and resistance compared with controls. Furthermore, several patient-related and disease-related factors were identified as angiopathy predictors. These results suggest that combined evaluation of CV surrogate markers may help detect subclinical organ damage and improve CV-risk classification in SLE.

RMD OpenVol. 11(4)
University of Crete (GR), Johannes Gutenberg University Mainz (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE), FORTH Institute of Molecular Biology and Biotechnology (GR), Hôpitaux Universitaires de Strasbourg (FR), Acura Kliniken (DE)
Good health and well-being
Openalex Percentile: Top 28%
Systemic Lupus Erythematosus Research
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