Functional connectivity dysregulation across the awareness continuum in Alzheimer's Disease: from hypernosognosia to anosognosia

These findings confirm that awareness levels within the AD continuum are associated with imbalances in the functional connectivity of the DMN, SN, and FPN. the recruitment of these networks follows a gradient across the awareness spectrum, providing critical insights into the neural underpinnings of awareness disruptions in Alzheimer's disease.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_101107
Primary Topic
Spatial Neglect and Hemispheric Dysfunction
Type
article
Field-Weighted Citation Impact
0.00
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article

Functional connectivity dysregulation across the awareness continuum in Alzheimer's Disease: from hypernosognosia to anosognosia

Riccardo Maramotti, Annalisa Chiari, Giovanna Zamboni, Giuseppe Pagnoni et al.
Alzheimer s & Dementia
Spatial Neglect and Hemispheric Dysfunction
article

Functional connectivity dysregulation across the awareness continuum in Alzheimer's Disease: from hypernosognosia to anosognosia

Riccardo Maramotti, Annalisa Chiari, Giovanna Zamboni, Giuseppe Pagnoni, Daniela Ballotta, Chiara Carbone, Chiara Gallingani, Manuela Tondelli
article en

Abstract

These findings confirm that awareness levels within the AD continuum are associated with imbalances in the functional connectivity of the DMN, SN, and FPN. the recruitment of these networks follows a gradient across the awareness spectrum, providing critical insights into the neural underpinnings of awareness disruptions in Alzheimer's disease.

Alzheimer s & DementiaVol. 21(S3)
University of Modena and Reggio Emilia (IT), University of Ferrara (IT), Azienda Ospedaliero-Universitaria di Modena (IT)
Openalex Percentile: Top 32%
Spatial Neglect and Hemispheric Dysfunction
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Functional connectivity dysregulation across the awareness continuum in Alzheimer's Disease: from hypernosognosia to anosognosia — Riccardo Maramotti, Annalisa Chiari, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS