Dynamic Functional Connectivity Changes in Subjective Cognitive Decline and Their Association with Spatial Navigation: A 5.0Tesla Ultra‐High Spatiotemporal Resolution fMRI Study

The findings of this study suggest that ultra-high spatiotemporal resolution fMRI using 5.0T MRI is an effective tool for investigating DFC changes in SCD. Alterations in DFC temporal properties in the SCD population may underlie early impairments in spatial navigation functions and can serve as sensitive neuroimaging biomarkers for the preclinical detection of AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_098138
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Dynamic Functional Connectivity Changes in Subjective Cognitive Decline and Their Association with Spatial Navigation: A 5.0Tesla Ultra‐High Spatiotemporal Resolution fMRI Study

Futao Chen, Bing Zhang, Qian Chen, Xiang Fan
Alzheimer s & Dementia
Functional Brain Connectivity Studies
article

Dynamic Functional Connectivity Changes in Subjective Cognitive Decline and Their Association with Spatial Navigation: A 5.0Tesla Ultra‐High Spatiotemporal Resolution fMRI Study

Futao Chen, Bing Zhang, Qian Chen, Xiang Fan
article en

Abstract

The findings of this study suggest that ultra-high spatiotemporal resolution fMRI using 5.0T MRI is an effective tool for investigating DFC changes in SCD. Alterations in DFC temporal properties in the SCD population may underlie early impairments in spatial navigation functions and can serve as sensitive neuroimaging biomarkers for the preclinical detection of AD.

Alzheimer s & DementiaVol. 21(S2)
Nanjing Drum Tower Hospital (CN), Peking University Shenzhen Hospital (CN)
Openalex Percentile: Top 32%
Functional Brain Connectivity Studies
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