The neural correlates of sustained attention in Dementia with Lewy Bodies patients: a task‐based fMRI study
DLB patients performed poorly on tasks within the attentive and visuo-spatial domains. Slower reaction times in the DLB group were associated with decreased activation in cuneus and precuneus. These data confirm the central role of these brain areas in sustained attention, one of the primary components of attention, as previously shown in healthy young participants [3]. Further studies with larger DLB populations are needed to confirm the functional mechanisms underlying the various components of attentive deficits typically experienced by these patients. Acknowledgement: This study has been supported by the Italian Ministry of Health (#GR-2019-12369242) and by #NEXTGENERATIONEU, project MNESYS (PE0000006).
Authors
- Annalisa Bosco
- Lucia Guidi (ORCID: https://orcid.org/0000-0002-2472-720X)
- Luisa Sambati (ORCID: https://orcid.org/0000-0002-5939-7933)
- Elettra Capogna (ORCID: https://orcid.org/0000-0002-8847-2461)
- Annalena Venneri
- Caterina Tonon
- Raffaele Lodi
- Davide Braghittoni
- Micaela Mitolo
- Greta Venturi
Institutions
- University of Parma (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_102709
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute