Effect of smoking on drug-resistant tuberculosis treatment outcomes and potential mechanistic pathways: a multicountry cohort study
People who smoked had a lower frequency of MDR/RR-TB treatment success than those who did not smoke. Eliminating loss to follow-up reduced this difference by smoking status, suggesting that pathways related to retention in treatment were a major driver of this disparity.
Authors
- Aga Krisnanda
- Letizia Trevisi (ORCID: https://orcid.org/0009-0006-9814-0563)
- Matthew L. Romo (ORCID: https://orcid.org/0000-0002-3038-0644)
- Palwasha Khan (ORCID: https://orcid.org/0000-0002-0873-8355)
- Ohanna Kirakosyan
- Helena Huerga (ORCID: https://orcid.org/0000-0003-0302-9063)
- Mathieu Bastard (ORCID: https://orcid.org/0000-0002-4296-8867)
- Lawrence Oyewusi
- Atyrkul Toktogonova
- Carole Diane Mitnick (ORCID: https://orcid.org/0000-0002-3455-658X)
- Michael Rich (ORCID: https://orcid.org/0000-0003-4333-4695)
- Muhammad Rafi Siddiqui
- Shrivani Padayachee
- Molly Forrest Franke (ORCID: https://orcid.org/0000-0002-4890-5728)
- Helen R. Stagg (ORCID: https://orcid.org/0000-0003-4022-3447)
- Mahmud Rashitov
- Cathy Hewison
- Girma Tefera
- Camilo Gómez-Restrepo
- Allison LaHood
- Edwin Herrera Flores
- Tina Kotrikadze
Institutions
- Brigham and Women's Hospital (US)
- Partners In Health (US)
- Harvard University (US)
- London School of Hygiene & Tropical Medicine (GB)
- Hospital Nacional Cayetano Heredia (PE)
- Chest Diseases Hospital (KW)
- Myanmar Oxford Clinical Research Unit (MM)
- Ministry of Health of Kyrgyzstan (KG)
- National Center of Cardiology and Internal Medicine (KG)
- Médecins Sans Frontières (US)
- Interactive Research and Development (PK)
- Harvard Global Health Institute (US)
- Médecins Sans Frontières (FR)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjresp-2025-003777
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00