Functional Connectome Signatures of Patients with Asymptomatic and Typical Alzheimer's

This study underscores the utility of fMRI-based techniques for elucidating connectivity differences in asymptomatic and symptomatic stages of AD. By mapping out network-level alterations, the resulting brain graphs offer valuable insights into the pathophysiology of AD, highlighting regions and pathways that may be critical in the early detection and treatment of the disease, potentially in a clinical setting utilizing fMRI as a biomarker.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_103445
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Functional Connectome Signatures of Patients with Asymptomatic and Typical Alzheimer's

K. Huang, Yijie Wang, Yi Fang Zhao, Xiaoqing Huang et al.
Alzheimer s & Dementia
Functional Brain Connectivity Studies
article

Functional Connectome Signatures of Patients with Asymptomatic and Typical Alzheimer's

K. Huang, Yijie Wang, Yi Fang Zhao, Xiaoqing Huang, Dayu Sun, Rishit Puri, Jie Zhang
article en

Abstract

This study underscores the utility of fMRI-based techniques for elucidating connectivity differences in asymptomatic and symptomatic stages of AD. By mapping out network-level alterations, the resulting brain graphs offer valuable insights into the pathophysiology of AD, highlighting regions and pathways that may be critical in the early detection and treatment of the disease, potentially in a clinical setting utilizing fMRI as a biomarker.

Alzheimer s & DementiaVol. 21(S2)
Indiana University Bloomington (US), Agri Processing Services (United States) (US), Richard M. Fairbanks Foundation (US), Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 32%
Functional Brain Connectivity Studies
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