Inhibited FSH Alterations On Alzheimer'S Disease Rodent Models: Focus on tau and Amyloid Beta Expression

Our results suggest that inhibited FSH gave rise to a down regulated Tau protein expression, on the contrary an upregulation in the expression of amyloid-beta was observed. These findings raises our interests on reproductive hormonal interplay in AD, more studies are needed to understand the role of follicle stimulating hormone in menarche which may impact on the occurrence of AD in women.