Evaluation of biomarkers sTREM-1, procalcitonin and C reactive protein in the diagnosis of pleural infection
The study demonstrated higher sTREM-1, PCT and CRP levels in empyema and CPPE and lower levels in transudates. Both sTREM-1 and CRP showed a higher than 70% diagnostic accuracy between infectious and non-infectious pleural effusions and between CPPE and UPPE; however, not superior to LDH pleural fluid levels.
Authors
- Carlos Sérgio Rocha Silva (ORCID: https://orcid.org/0000-0002-3367-9502)
- Lisete R. Teixeira (ORCID: https://orcid.org/0000-0001-9148-7368)
- P.F.B. Colares
- Evaldo Marchi
- Milena Marques Pagliarelli Acencio
- Roberta Karla Barbosa Sales
- Vanessa Adelia Alvarenga
Institutions
- Faculdade de Medicina de Jundiaí (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjresp-2024-002763
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00