Functional and Emotional Predictors of Cognitive Decline: Insights from the ADNI Dataset
The current findings demonstrate that baseline functional and emotional measures can predict future cognitive decline, with functional difficulties (FAQ) contributing the most, followed by depressive symptoms (GDS), and hippocampal volume (HIPPO). These results suggest that functional and emotional measures vary alongside cognitive decline, with neuroimaging offering complementary insights when combined with behavioral evaluations for early detection.
Authors
- Nicola Sambuco (ORCID: https://orcid.org/0000-0001-8941-1049)
- Daphne Gasparre
- L. Antonucci
- Aurora Bonvino (ORCID: https://orcid.org/0000-0001-8772-5992)
- Giorgia Francesca Scaramuzzi
- Ester Cornacchia
- Paolo Taurisano
- Giulio Pergola
Institutions
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_100984
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00