Regional Brain Volume and Thickness in Mild Behavioral Impairment‐Apathy

MBI-apathy shows stronger stronger associations with atrophy in regions affected early in the course of AD. This finding suggests that at the CN and MCI stages, MBI-apathy may reflect brain changes characteristic of early AD. These findings suggest that MBI-apathy is associated with early-stage AD and that regions typically linked to apathy are likely affected later in the disease, with stronger associations emerging as AD progresses.