Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

The bidirectional albeit small mediation effect suggests that gray matter atrophy and irregular/fragmented sleep influence each other to negatively affect cognition in community-dwelling older adults.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_097781
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

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Alzheimer s & Dementia
Sleep and related disorders
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Bidirectional Mediation Effects of Sleep and Brain Volume on Cognition in Older Adults

Woon‐Puay Koh, Juan Helen Zhou, Kwun Kei Ng, XinYu Chua, Shuo Qin, ChunSiong Soon, Michael Wei‐Liang Chee
article en

Abstract

The bidirectional albeit small mediation effect suggests that gray matter atrophy and irregular/fragmented sleep influence each other to negatively affect cognition in community-dwelling older adults.

Alzheimer s & DementiaVol. 21(S2)
National University of Singapore (SG)
Quality Education
Openalex Percentile: Top 29%
Sleep and related disorders
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