Potential steric blockers of interaction between β‐secretase and mutant forms of APP

During the work, we selected peptides that had the greatest versatility as blockers to three forms of APP. To confirm their effectiveness, in vitro and in vivo studies are necessary.

Authors

M. S. Kastsiuchenka (ORCID: https://orcid.org/0009-0000-9121-6680)
Tatsiana Khrustaleva

Institutions

Institute of Physiology National Academy of Sciences of Belarus (BY)
Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus (BY)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2025-12-01
DOI: https://doi.org/10.1002/alz70855_107048
Primary Topic: Alzheimer's disease research and treatments
Type: article
Field-Weighted Citation Impact: 0.00

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article

Potential steric blockers of interaction between β‐secretase and mutant forms of APP

M. S. Kastsiuchenka, Tatsiana Khrustaleva

Dec 1, 2025

Alzheimer s & Dementia

Alzheimer's disease research and treatments

article

Potential steric blockers of interaction between β‐secretase and mutant forms of APP

M. S. Kastsiuchenka, Tatsiana Khrustaleva

December 1, 2025article en

Abstract

During the work, we selected peptides that had the greatest versatility as blockers to three forms of APP. To confirm their effectiveness, in vitro and in vivo studies are necessary.

Alzheimer s & DementiaVol. 21(S1)

Institute of Physiology National Academy of Sciences of Belarus (BY), Institute of Chemistry of New Materials of the National Academy of Sciences of Belarus (BY)

Openalex Percentile: Top 33%

Alzheimer's disease research and treatments

DOI Open Access PDF OpenAlex

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Potential steric blockers of interaction between β‐secretase and mutant forms of APP — M. S. Kastsiuchenka, Tatsiana Khrustaleva · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS