The Association between Mild Behavioral Impairment and Frailty in the setting of Pure Amyloid‐ß and Mixed Pathology in the Southeast Asian BIOCIS Study
Findings highlight a significant association between MBI and frailty among symptomatic at-risk individuals having mixed vascular-amyloid pathology; worse MBI increasing the likelihood of prefrailty. This association highlights a potential behavioural basis for the detection of and/or intervention for cognitive impairment, warranting further investigation.
Authors
- Jacklyn Leonardo (ORCID: https://orcid.org/0000-0003-0878-8149)
- Ashwati Vipin (ORCID: https://orcid.org/0000-0002-3575-7287)
- Gurveen Kaur Sandhu
- Gaurav Bhalla (ORCID: https://orcid.org/0000-0003-0337-3809)
- Kiirtaara Aravindhan (ORCID: https://orcid.org/0000-0002-8941-1679)
- Smriti Ghildiyal (ORCID: https://orcid.org/0009-0007-7765-3551)
- Pricilia Tanoto (ORCID: https://orcid.org/0009-0002-5456-690X)
- Kai En Leong
- Nagaendran Kandiah
- Bocheng Qiu (ORCID: https://orcid.org/0009-0005-3255-7027)
- Reza Salim
- Shan Yao Liew
- Xin Ying Sim
- Fatin Zahra Zailan
- Faith Phemie Hui En Lee
- Yi Jin Leow
Institutions
- Nanyang Technological University (SG)
- NIL Technology (Denmark) (DK)
- Singapore Centre for Environmental Life Sciences Engineering (SG)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_100635
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00