The Neuroprotective potentiality of β‐hydroxy β‐methyl butyrate in an Alzheimer's disease mouse model
According to our findings, HMB promotes synaptic protein expression and regulates CREB phosphorylation, potentially regulating brain plasticity and leading to cognitive recovery in AD models. Finally, our results suggested that the HMB is a strong and safe supplement, more investigation on its potential benefits for treating Alzheimer's appears to be desirable.
Authors
- Ramesh Kumar Paidi (ORCID: https://orcid.org/0000-0003-3340-8056)
- Kalipada Pahan
Institutions
- Rush University Medical Center (US)
- Jesse Brown VA Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_098487
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00