Evaluating Amyloid Pathology and Cognitive Outcomes in AD: Insights from CERAD and Thal Staging
CERAD scores were associated with cognition, while Thal scores were not. However, after adjusting for Braak NFT, this association was no longer significant, suggesting that the frequency of amyloid deposits may have a closer correlation with neurofibrillary tangles classification than Thal staging.
Authors
- Lea T. Grinberg (ORCID: https://orcid.org/0000-0002-6809-0618)
- Renata Elaine Paraízo Leite (ORCID: https://orcid.org/0000-0002-5878-398X)
- Eduardo Ferriolli (ORCID: https://orcid.org/0000-0002-5028-2451)
- Vítor Ribeiro Paes (ORCID: https://orcid.org/0000-0001-8752-5624)
- Cláudia Kimie Suemoto (ORCID: https://orcid.org/0000-0002-5942-4778)
- Ricardo Nitrini
- Alberto Fernando Oliveira Justo
- Carlos Augusto Pasquallucci
Institutions
- Universidade de São Paulo (BR)
- University of California, San Francisco (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100810
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00