Choroid Plexus Volume in Pathologically Confirmed Alzheimer's Disease

Given existing evidence that impaired clearance is related to AD-pathology, and CP's involvement in clearance, our findings suggest we can detect morphological changes (via CP-Volume changes) related to these processes. This warrants further investigation longitudinally and supports the feasibility of sMRI in assessing CP as a correlate of pathological burden.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_101146
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Choroid Plexus Volume in Pathologically Confirmed Alzheimer's Disease

Nathan W. Churchill, Adrienne Lloyd Atayde, Avyarthana Dey, Marc A. Khoury et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Choroid Plexus Volume in Pathologically Confirmed Alzheimer's Disease

Nathan W. Churchill, Adrienne Lloyd Atayde, Avyarthana Dey, Marc A. Khoury, DG Munoz, Corinne E. Fischer, Tom A. Schweizer, Francis A Fernandes
article en

Abstract

Given existing evidence that impaired clearance is related to AD-pathology, and CP's involvement in clearance, our findings suggest we can detect morphological changes (via CP-Volume changes) related to these processes. This warrants further investigation longitudinally and supports the feasibility of sMRI in assessing CP as a correlate of pathological burden.

Alzheimer s & DementiaVol. 21(S2)
St. Michael's Hospital (CA), University of Toronto (CA), Toronto Metropolitan University (CA)
Openalex Percentile: Top 33%
Dementia and Cognitive Impairment Research
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