Archetypal analysis quantifies changes in patterns of visual field loss in eyes with acute non-arteritic anterior ischaemic optic neuropathy
AA effectively quantifies distinct, clinically significant VF spatial loss patterns in NAION, revealing significant temporal changes and demographic differences. Global VF loss represents the predominant AT, increasing notably within 2 months of disease onset. Prominent racial disparities, particularly higher severity in Asian individuals, underscore potential differences in NAION aetiology or susceptibility. These findings provide a foundation for improved disease characterisation and prognosis.
Authors
- Jui‐Kai Wang (ORCID: https://orcid.org/0000-0001-8308-8455)
- MICHAEL WALL
- Brian Woods
- Tobias Elze (ORCID: https://orcid.org/0000-0002-2032-0496)
- Mark J. Kupersmith
- David Szanto (ORCID: https://orcid.org/0000-0002-4640-4655)
Institutions
- University of Iowa (US)
- Massachusetts Eye and Ear Infirmary (US)
- Ollscoil na Gaillimhe – University of Galway (IE)
- New York Eye and Ear Infirmary (US)
- University Hospital Galway (IE)
- COPE Galway (IE)
- The University of Texas Southwestern Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- British Journal of Ophthalmology
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1136/bjo-2025-328673
- Citations
- 1
- Primary Topic
- Intraoperative Neuromonitoring and Anesthetic Effects
- Type
- article
- Field-Weighted Citation Impact
- 2.01