Localizing Objective versus Subjective Cognition in Preclinical Alzheimer's Disease Using Atrophy Network Mapping
We identified distinct brain networks associated with transitional objective and subjective cognition in preclinical AD using atrophy network mapping. These findings help elucidate early pathophysiology of AD and extend the use of this approach, previously applied to AD dementia, to localize transitional cognitive signs and symptoms in preclinical AD.
Authors
- Sheena Baratono (ORCID: https://orcid.org/0000-0003-4760-607X)
- Shan H. Siddiqi (ORCID: https://orcid.org/0000-0002-0967-9289)
- Nancy J. Donovan (ORCID: https://orcid.org/0000-0002-6328-1589)
- Benjamin S. Zide (ORCID: https://orcid.org/0009-0003-5621-8850)
- Stephan Palm (ORCID: https://orcid.org/0009-0000-8345-5470)
- S. Lee (ORCID: https://orcid.org/0000-0002-9223-8512)
- Grace Burt
- William J Drew
- Nicole Chiulli
- Michael D Fox
- Reisa A. Sperling
Institutions
- Brigham and Women's Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_099126
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00