Distinct cortical inhibitory profiles in schizophrenia and bipolar disorder: A TMS-EEG study of GABAb function
Our data support the existence of a functional inhibitory deficit mediated by GABAb receptors in schizophrenia, that is associated with cognitive performance and symptoms. In the context of existing literature, this deficit may characterize a subgroup of patients with this diagnosis.
Authors
- Ramírez Sierra
- Gema Mijancos-Martínez
- Emma Osorio-Iriarte
- Saúl J. Ruiz-Gómez (ORCID: https://orcid.org/0000-0003-1483-2265)
- Claudia Rodríguez-Valbuena
- Juan Carlos Fiorini-Talavera
- Alejandro Roig
- Vicente Molina
- Ricardo D. Mancha
- Inés Fernández-Linsenbarth
- Alejandro Bachiller
- Miguel Angel Mañanas
Institutions
- Universidad de Valladolid (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Hospital Clínico Universitario de Valladolid (ES)
- Universitat Politècnica de Catalunya (ES)
Publication Details
- Journal
- Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1016/j.pnpbp.2025.111593
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00