The Alzheimer's Cell Atlas: A comprehensive brain single‐cell transcriptomic atlas using a generative AI foundation model
This study generated a large-scale human brain snRNA-seq atlas focused on neurodegenerative diseases, providing a valuable digital resource for the scientific community to explore multiple neurodegenerative conditions from diverse perspectives.
Authors
- Yuan Hou (ORCID: https://orcid.org/0000-0002-3900-6122)
- Yunguang Qiu (ORCID: https://orcid.org/0000-0002-5094-0936)
- Jielin Xu
- Andrew A. Pieper
- Lijun Dou
- Noah J Lorincz‐Comi
- Feixiong Cheng
- Yadi Zhou
Institutions
- Cleveland Clinic (US)
- University Hospitals Cleveland Medical Center (US)
- Louis Stokes Cleveland VA Medical Center (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107196
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00