Markers of leucine‐rich repeat kinase 2 activity are associated with pathological protein aggregation across neurodegenerative diseases
In conclusion, phosphorylation of Rab proteins by LRRK2 may play a role in pathological tau and GVB accumulation across neurodegenerative diseases.
Authors
- Todd J. Cohen (ORCID: https://orcid.org/0000-0002-4099-0278)
- Shih‐Hsiu J. Wang (ORCID: https://orcid.org/0000-0002-0358-8159)
- John F. Ervin (ORCID: https://orcid.org/0000-0002-4446-0231)
- Silas A. Buck (ORCID: https://orcid.org/0000-0002-9476-9210)
- Laurie H Sanders
Institutions
- University of North Carolina at Chapel Hill (US)
- Duke Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107317
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00