Diagnostic biomarker potential of plasma small extracellular vesicle RNA enriched for microglial origin in people with Dementia with Lewy bodies
Neuroinflammation-focused plasma SEV RNA can help distinguishing DLB from AD accurately. We will develop a bespoke multiplex plasma SEV RNA assay using the identified differentially expressed RNA and will evaluate its diagnostic accuracy in an independent cohort.
Authors
- Fatma Büşra Işık (ORCID: https://orcid.org/0009-0009-3237-3120)
- Helen Miranda Knight (ORCID: https://orcid.org/0000-0003-3267-9591)
- Anto P. Rajkumar (ORCID: https://orcid.org/0000-0003-3203-6326)
Institutions
- University of Nottingham (GB)
- Nottinghamshire Healthcare NHS Foundation Trust (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_098303
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00