Systematic review and meta‐analysis of Alzheimer’s disease clinical trial results over more than a quarter century (1994‐2025) ‐ overall evidence and time savings
Success and failure of Alzheimer's treatments is partly obscured by including only one of three domains of clinical efficacy: cognition, function and global. True treatment efficacy and true lack of efficacy are much easier to detect with combined outcomes.
Authors
- Suzanne Hendrix (ORCID: https://orcid.org/0000-0002-2374-7727)
- Craig Mallinckrodt
- Benjamin Haaland (ORCID: https://orcid.org/0000-0002-6270-6303)
- Kent Hendrix
- Newman Knowlton
- Samuel P. Dickson (ORCID: https://orcid.org/0000-0002-4622-1349)
- Patrick P O'Keefe
Institutions
- TetraLogic Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_100006
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00