Superficial Cortical Aβ Clearance and ARIA Pathology in Aducanumab‐Treated Alzheimer's Disease
Aβ clearance and ARIA-related findings were localized predominantly in superficial cortical layers, suggesting that aducanumab biodistribution is more pronounced in these regions rather than deeper cortical layers.
Authors
- Dennis W. Dickson (ORCID: https://orcid.org/0000-0001-7189-7917)
- Derek Richard Johnson (ORCID: https://orcid.org/0000-0002-4217-5517)
- Jonathan Graff‐Radford
- Matthew H. Rutledge
- Christina M. Moloney (ORCID: https://orcid.org/0000-0002-4258-2294)
- Aivi T. Nguyen (ORCID: https://orcid.org/0000-0003-1809-9451)
- Yoav D. Piura (ORCID: https://orcid.org/0000-0003-1004-4560)
- Jessica L Chalk (ORCID: https://orcid.org/0000-0002-3564-2375)
- Sarah Lincoln
- Melissa E. Murray
- D S Knopman
- Baayla D.C. Boon
- Neill R. Graff‐Radford
- R. Ross Reichard
Institutions
- Jacksonville College (US)
- WinnMed (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_105890
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00