Donepezil‐Induced Severe Anorexia and T‐Wave Inversion in Early‐Onset Alzheimer's Disease: A Case Report

Donepezil hydrochloride, used to treat Alzheimer's disease, is typically initiated at a low dose and titrated to minimize gastrointestinal side effects. Despite its favorable safety profile, the patient developed severe anorexia, dehydration, and electrocardiographic abnormalities. This case highlights the need for individualized dosing and careful monitoring of caregivers during pharmacotherapy.

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Publication Details

Journal
Clinical Case Reports
Published
2025-12-25
DOI
https://doi.org/10.1002/ccr3.71660
Citations
1
Primary Topic
Dysphagia Assessment and Management
Type
article
Field-Weighted Citation Impact
3.12
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article

Donepezil‐Induced Severe Anorexia and T‐Wave Inversion in Early‐Onset Alzheimer's Disease: A Case Report

Takeshi Kuroda, Nobuyuki Takahashi, Hidetomo Murakami, H. TANAKA et al.
1 citations
Clinical Case Reports
Dysphagia Assessment and Management
3.12
article

Donepezil‐Induced Severe Anorexia and T‐Wave Inversion in Early‐Onset Alzheimer's Disease: A Case Report

Takeshi Kuroda, Nobuyuki Takahashi, Hidetomo Murakami, H. TANAKA, Takashi Yoshioka
article en
1 citations

Abstract

Donepezil hydrochloride, used to treat Alzheimer's disease, is typically initiated at a low dose and titrated to minimize gastrointestinal side effects. Despite its favorable safety profile, the patient developed severe anorexia, dehydration, and electrocardiographic abnormalities. This case highlights the need for individualized dosing and careful monitoring of caregivers during pharmacotherapy.

Clinical Case ReportsVol. 14(1)
SHOWA Medical University (JP), SHOWA Medical University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 6%
Dysphagia Assessment and Management
3.12
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