Therapeutic Effects of Phytoestrogen Naringenin in Polycystic Ovary Syndrome (PCOS): Involvement of Kisspeptin and Calcitonin Gene Related Peptide Signalling Pathways
Naringenin may ameliorate PCOS by downregulating hypothalamic <i>Kiss1</i> and <i>Cgrp</i> gene expression in rats. These results suggest a novel mechanism of naringenin's action and highlight its potential for clinical application.
Authors
- Fariba Mahmoudi (ORCID: https://orcid.org/0000-0001-6092-1352)
- Habibi Manizheh
- Khadijeh Haghighat (ORCID: https://orcid.org/0000-0002-9016-3086)
- Homayoun khazali
Institutions
- Shahid Beheshti University (IR)
- University of Mohaghegh Ardabili (IR)
Publication Details
- Journal
- Reports of Biochemistry and Molecular Biology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.61882/rbmb.14.1.38
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Mohaghegh Ardabili