Wall shear stress and oscillatory shear index are independently associated with complicated carotid artery plaques
In patients with up to 80% ICA stenosis, male gender, elevated systolic WSS and reduced OSI were independently associated with the presence of cCAP, with group differences noted for ICA/CCA ratio. Our findings highlight the importance of geometric and haemodynamic biomarkers for individual stroke risk stratification.
Authors
- Christine Contini (ORCID: https://orcid.org/0000-0002-6399-4394)
- Horst Urbach (ORCID: https://orcid.org/0000-0001-7264-4807)
- Christoph Strecker (ORCID: https://orcid.org/0000-0001-5383-9369)
- Anja Hennemuth (ORCID: https://orcid.org/0000-0002-0737-7375)
- Gregor Hoermann (ORCID: https://orcid.org/0000-0002-7374-4380)
- Ernst Mayerhofer (ORCID: https://orcid.org/0000-0001-8902-4209)
- Hansjörg Mast (ORCID: https://orcid.org/0009-0008-3744-7304)
- Jonathan Andrae
- Andreas Harloff (ORCID: https://orcid.org/0000-0002-3252-7910)
- Andreas Schindler (ORCID: https://orcid.org/0000-0003-0183-5782)
- Dominik Obrist
- Karl Winkler
- Ali Mokhtari (ORCID: https://orcid.org/0009-0004-2567-9256)
- Jörg Sahlmann
- Michael M Hoffmann
Institutions
- University of Bern (CH)
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
- LMU Klinikum (DE)
- Munich Leukemia Laboratory (Germany) (DE)
- German Centre for Cardiovascular Research (DE)
- Fraunhofer Institute for Digital Medicine (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Imaging
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1093/ehjci/jeaf366
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00