Systemic delivery of anti‐sense oligonucleotide targeting α‐synuclein for the treatment of multiple systems atrophy

Thus, we have successfully alleviated some of the pathology associated with MSA in a mouse model; however, without direct delivery to oligodendrocytes, other approaches may need to supplement this therapy.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_105773
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Systemic delivery of anti‐sense oligonucleotide targeting α‐synuclein for the treatment of multiple systems atrophy

Robert A. Rissman, Brian Spencer
Alzheimer s & Dementia
Parkinson's Disease Mechanisms and Treatments
article

Systemic delivery of anti‐sense oligonucleotide targeting α‐synuclein for the treatment of multiple systems atrophy

Robert A. Rissman, Brian Spencer
article en

Abstract

Thus, we have successfully alleviated some of the pathology associated with MSA in a mouse model; however, without direct delivery to oligodendrocytes, other approaches may need to supplement this therapy.

Alzheimer s & DementiaVol. 21(S1)
University of Southern California (US), Autism Research Institute (US)
Openalex Percentile: Top 31%
Parkinson's Disease Mechanisms and Treatments
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Systemic delivery of anti‐sense oligonucleotide targeting α‐synuclein for the treatment of multiple systems atrophy — Robert A. Rissman, Brian Spencer · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS