Objective sleep quality and MRI biomarkers of Alzheimer's Disease in a diverse cohort of older adults

Nighttime sleep duration>8 hours and poor sleep quality, including longer TIB, WASO, and awakening length, were associated with worse AD-related MRI patterns among diverse community-dwelling older adults. Future longitudinal studies are warranted to validate the pathophysiological mechanisms underlying those sleep-AD associations.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_098275
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
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article

Objective sleep quality and MRI biomarkers of Alzheimer's Disease in a diverse cohort of older adults

Meredith N. Braskie, Clémence Cavaillès, Xiaodi Liu, Yue Leng et al.
Alzheimer s & Dementia
Sleep and related disorders
article

Objective sleep quality and MRI biomarkers of Alzheimer's Disease in a diverse cohort of older adults

Meredith N. Braskie, Clémence Cavaillès, Xiaodi Liu, Yue Leng, Katie L Stone, Kristine Yaffe
article en

Abstract

Nighttime sleep duration>8 hours and poor sleep quality, including longer TIB, WASO, and awakening length, were associated with worse AD-related MRI patterns among diverse community-dwelling older adults. Future longitudinal studies are warranted to validate the pathophysiological mechanisms underlying those sleep-AD associations.

Alzheimer s & DementiaVol. 21(S2)
University of Southern California (US), University of California, San Francisco (US), California Pacific Medical Center (US)
Openalex Percentile: Top 29%
Sleep and related disorders
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