Impact of Worry on Experimental Hippocampal Tasks and Hippocampal Volumetrics in Older Adults with Subjective Cognitive Complaints

Older adults with SCC worry exhibit higher levels of mood and motivation symptoms, which may contribute to poorer performance on cognitive tasks. Two hypotheses are possible: 1) greater mood symptoms are driving SCC and ARENA performance, or 2) ARENA may be uniquely sensitive to detect memory changes, as its neural correlates are implicated in early AD. Since mood symptoms are common in preclinical AD, the worried SCC group may reflect this preclinical change.