Application of RNA sequencing to cause-of-death investigation: A pilot study

This proof-of-concept pilot study suggests that RNA-seq can capture molecular signatures associated with specific causes of death. These findings indicate the potential of transcriptomic profiling as a complementary tool in forensic diagnostics when conventional methods are inconclusive.

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Publication Details

Journal
Legal Medicine
Published
2025-12-25
DOI
https://doi.org/10.1016/j.legalmed.2025.102772
Primary Topic
Forensic Entomology and Diptera Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Application of RNA sequencing to cause-of-death investigation: A pilot study

Masataka Nagao, Takafumi Nagao, Akira Namera, Naoki Nakao et al.
Legal Medicine
Forensic Entomology and Diptera Studies
article

Application of RNA sequencing to cause-of-death investigation: A pilot study

Masataka Nagao, Takafumi Nagao, Akira Namera, Naoki Nakao, Takahiro Harada, Kazuhiro Murata
article en

Abstract

This proof-of-concept pilot study suggests that RNA-seq can capture molecular signatures associated with specific causes of death. These findings indicate the potential of transcriptomic profiling as a complementary tool in forensic diagnostics when conventional methods are inconclusive.

Legal MedicineVol. 80
Hiroshima University (JP)
Good health and well-being
Openalex Percentile: Top 31%
Forensic Entomology and Diptera Studies
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Application of RNA sequencing to cause-of-death investigation: A pilot study — Masataka Nagao, Takafumi Nagao, et al. · Legal Medicine (2025) | TGRS Research Map | TGRS