Heterogeneity and progression of amyloid and vascular injury in Alzheimer's and Mixed dementia cohorts
In the mixed subtype, which is likely the most common subtype in memory clinics and community-based samples, amyloid was associated with WMH volume at baseline, but greater free-water levels predicted WMH growth over time.
Authors
- Phillip H. Kuo (ORCID: https://orcid.org/0000-0002-4957-8298)
- Eric Edward Smith (ORCID: https://orcid.org/0000-0003-3956-1668)
- Nesrine Rahmouni
- Frank S. Prato (ORCID: https://orcid.org/0000-0002-4592-2522)
- Katrina Carver (ORCID: https://orcid.org/0000-0001-5378-373X)
- Eric Yin (ORCID: https://orcid.org/0000-0002-9526-7490)
- Andrew Clappison (ORCID: https://orcid.org/0000-0003-3766-4452)
- Erin Gibson (ORCID: https://orcid.org/0000-0001-5823-0173)
- Katherine Zukotynski (ORCID: https://orcid.org/0000-0003-0584-4387)
- Miracle Ozzoude (ORCID: https://orcid.org/0000-0003-4154-2765)
- Maged Goubran (ORCID: https://orcid.org/0000-0001-5880-0818)
- Ging‐Yuek Robin Hsiung (ORCID: https://orcid.org/0000-0002-8017-0856)
- Julie Ottoy (ORCID: https://orcid.org/0000-0002-9879-7497)
- Joel Ramirez (ORCID: https://orcid.org/0000-0002-5582-1776)
- Stephanie Berberian
- Ginelle Feliciano
- Christopher J.M. Scott (ORCID: https://orcid.org/0000-0002-3236-7523)
- Lauren Abby Woods
- Jean‐Claude Tardif
- Fuqiang Gao
- Jean‐Paul Soucy
- Robert Laforce
- Pedro Rosa‐Neto
- Sandra E. Black
- Walter Swardfager
- Min Su Kang
Institutions
- Western University (CA)
- Montreal Neurological Institute and Hospital (CA)
- Sunnybrook Health Science Centre (CA)
- University of Calgary (CA)
- University of Toronto (CA)
- Montreal Heart Institute (CA)
- Positive Living Society of British Columbia (CA)
- Banner - University Medical Center Tucson (US)
- Ontario Brain Institute (CA)
- Université Laval (CA)
- Hotchkiss Brain Institute (CA)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_100574
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00