The Association Between Platelet Mass Index and Morning Blood Pressure Surge in Newly Diagnosed Hypertensive Patients

Purpose: This study aimed to evaluate the relationship between Platelet Mass Index (PMI) and Morning Blood Pressure Surge (MBPS) in patients with newly diagnosed hypertension. Materials and Methods: A cross-sectional study was conducted between January and April 2025 at a tertiary cardiology outpatient clinic, including 158 hypertensive and 191 normotensive individuals. Blood pressure was monitored using Ambulatory Blood Pres-sure Monitoring (ABPM), and MBPS was calculated. PMI was derived by multiplying the platelet count by the mean platelet volume (MPV). The predictive ability of PMI for identifying elevated MBPS was assessed via receiver operating characteristic (ROC) curve analysis. Results: Systolic and diastolic blood pressure values across 24-hour, daytime, and nighttime measurements were significantly higher in the hypertensive group (all p28.2 mmHg showed significantly higher platelet count, PMI, PLR, and neutrophil levels (p