Communication is Key: Using Complex Co‐cultures to Decipher the Intercellular Crosstalk that Drives AD

Preliminary co-culture experiments emphasized the interconnectedness of the various neural cell types and the great potential of complex co-culture systems in understanding AD pathology. We believe that this work will contribute to the understanding of AD that will ultimately facilitate the development of effective therapeutic interventions.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_107155
Primary Topic
Pluripotent Stem Cells Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Communication is Key: Using Complex Co‐cultures to Decipher the Intercellular Crosstalk that Drives AD

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Alzheimer s & Dementia
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Communication is Key: Using Complex Co‐cultures to Decipher the Intercellular Crosstalk that Drives AD

Anders Smith, Doug Quackenbush, Gerald Wambua, Jimmy Elliott, Christopher Trussell, Brandon L. Taylor, Michaela Kneissel, Rebekah S. Decker, Frederick Lo, Maya Iskandar, Youngjae Woo, Veronica Roa, Katie Mao, Lang Huynh, Joe Siefert, Andrew Gunderson
article en

Abstract

Preliminary co-culture experiments emphasized the interconnectedness of the various neural cell types and the great potential of complex co-culture systems in understanding AD pathology. We believe that this work will contribute to the understanding of AD that will ultimately facilitate the development of effective therapeutic interventions.

Alzheimer s & DementiaVol. 21(S1)
Genomics Institute of the Novartis Research Foundation (US), Novartis (Switzerland) (CH)
Openalex Percentile: Top 36%
Pluripotent Stem Cells Research
DOIOpen Access PDFOpenAlex
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