Analysis of perivascular spaces highlights regional enlargement by sex, amyloid status, AD genetic predisposition and specific risk factors
These findings highlight sex- and disease stage-specific influence of risk factors on PVS, as well as the regional variability of these associations, underscoring the absence of an uniform brain-wide effect.
Authors
- Blanca Rodríguez‐Fernández (ORCID: https://orcid.org/0000-0002-5664-111X)
- Armand González Escalante
- Marta Cirach (ORCID: https://orcid.org/0000-0002-5518-1529)
- Jordi Huguet (ORCID: https://orcid.org/0000-0001-8420-4833)
- Tavia E. Evans (ORCID: https://orcid.org/0000-0003-2390-286X)
- Patricia Genius (ORCID: https://orcid.org/0000-0003-1836-5123)
- Natàlia Vilor‐Tejedor (ORCID: https://orcid.org/0000-0003-4935-6721)
- Arcadi Segura i Navarro
- Gonzalo Sánchez‐Benavides
- Oriol Grau‐Rivera
- Manel Esteller
- Alba Fernández‐Bonet
- David Vállez‐Garcia
- Mariateresa Buongiorno
- Mark Nieuwenhuijsen
Institutions
- Institució Catalana de Recerca i Estudis Avançats (ES)
- Radboud University Nijmegen (NL)
- Universitat Pompeu Fabra (ES)
- Instituto de Salud Carlos III (ES)
- Radboud University Medical Center (NL)
- Josep Carreras Leukaemia Research Institute (ES)
- Vall d'Hebron Institut de Recerca (ES)
- Pasqual Maragall Foundation (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Barcelonaβeta Brain Research Center (ES)
- Hospital Del Mar (ES)
- Institut de Biologia Evolutiva (ES)
- Centre for Genomic Regulation (ES)
- Barcelona Institute for Global Health (ES)
- Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (ES)
- Amsterdam University Medical Centers (NL)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_102667
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00