Neutrophil inflammation metrics are associated with the risk of future dementia in large‐scale electronic health record data from hospital systems
Our findings suggest that individuals with higher NLR are at greater risk of future AD/ADRD regardless of the study cohort or demographics, reinforcing the importance of peripheral inflammation and the need to clarify the mechanisms by which neutrophil biology influences AD pathology.
Authors
- Sean Jacobson (ORCID: https://orcid.org/0000-0001-9937-419X)
- Rebecca A. Betensky (ORCID: https://orcid.org/0000-0002-3793-1437)
- RS Osorio
- Omonigho M. Bubu (ORCID: https://orcid.org/0000-0001-7438-2628)
- Thomas Wisniewski
- Tovia Jacobs
- Ula Hwang
- Mark He
- Jaime Ramos Cejudo
Institutions
- NYU Langone Health (US)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107044
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00