Behavioral and Cellular Effects of Vitamin A Deficiency in a J20:RARE‐LacZ mouse model of Alzheimer's Disease
J20<sup>+/-</sup>:LacZ<sup>+/-</sup> mice aged 9-10 months display Aβ aggregation throughout the hippocampus and cortex, which may be responsible for local changes in ATRA signaling in the DG. Ongoing behavioral data analysis will give us additional information about the correlation between diet, behavioral performance, and AD pathology in the DG.
Authors
- Adam Baker (ORCID: https://orcid.org/0000-0003-0791-7324)
- Shane Smith (ORCID: https://orcid.org/0000-0002-7205-496X)
- Ashly Hindle
- Shadt Skawratananond
- J. Josh Lawrence
- Chhanda Bose
Institutions
- Texas Tech University (US)
- Lubbock Christian University (US)
- Translational Therapeutics (United States) (US)
- Texas Tech University Health Sciences Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106048
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00