Herpes Simplex Virus Type 1 DNA is associated with lower cognitive performance across multiple domains in Alzheimer's disease cases
These findings provide further evidence for the role of HSV-1 presence in AD pathogenesis and may exacerbate cognitive decline in individuals with AD.
Authors
- Congcong Zhu (ORCID: https://orcid.org/0000-0002-0143-7453)
- Timothy J. Hohman (ORCID: https://orcid.org/0000-0002-3377-7014)
- Marlene Tejeda
- William S. Bush (ORCID: https://orcid.org/0000-0002-9729-6519)
- John J. Farrell (ORCID: https://orcid.org/0000-0001-6502-1572)
- Lee M. Wetzler (ORCID: https://orcid.org/0000-0002-6596-2986)
- Eden R. Martin (ORCID: https://orcid.org/0000-0002-4035-9152)
- Kathryn L. Lunetta (ORCID: https://orcid.org/0000-0002-9268-810X)
- Lindsay AA. Farrer
- Gerald D. Schellenberg
- Li‐San Wang
- Margaret Pericak‐Vance
- Richard Sherva
- Jonathan L Haines
- Paul K Crane
- Shubhabrata Mukherjee
- Jesse Mez
Institutions
- Boston University (US)
- University of Miami (US)
- University of Washington (US)
- Dr. John T. Macdonald Foundation (US)
- Boston Public Schools (US)
- Case Western Reserve University (US)
- University of Pennsylvania (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_106840
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00