Repeated Dextran Sulfate Sodium Exposure Elicits Distinct Immune Responses Reflecting Human Ulcerative Colitis
Collectively, our data indicate that repeated DSS cycles provide a better experimental colitis model for studying immune cells in UC and identifying distinct immune subtypes relevant to UC therapeutics.
Authors
- Joshua B. Wechsler (ORCID: https://orcid.org/0000-0002-1275-3275)
- Ankur D Naqib (ORCID: https://orcid.org/0000-0003-0832-5646)
- Caroline J. Herrnreiter (ORCID: https://orcid.org/0000-0002-6345-3758)
- Xingsheng Ren
- Anastasiia Serdiukova
- Ronen Sumagin
- Maya E. Sumagin
- Zeinab Dehghani
- Stefan Green
- Laura D. Manzanares
Institutions
- Northwestern University (US)
- Rush University Medical Center (US)
- Lurie Children's Hospital (US)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101714
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00