Spatial atrophy subtypes are associated with specific sociodemographic, comorbidity, pathologic, and cognitive factors in a representative community‐based cohort: a HABS‐HD study
Although a greater proportion of diverse groups demonstrate atrophy, spatial subtypes are generalizable to the general population and are associated with distinct pathologic and cognitive profiles. Clinical outcomes and response to treatment may vary by atrophy subtype and can inform clinical trials and precision-medicine efforts.
Authors
- Meredith N. Braskie (ORCID: https://orcid.org/0000-0002-6439-4243)
- Aristeidis Sotiras (ORCID: https://orcid.org/0000-0003-0795-8820)
- Karin L. Meeker (ORCID: https://orcid.org/0000-0002-2677-5715)
- Beau M. Ances (ORCID: https://orcid.org/0000-0003-3862-7397)
- Gordon An
- Sid E. O'Bryant
- Ann D Cohen
- Brian A. Gordon
- Arthur W. Toga
Institutions
- University of Southern California (US)
- University of North Texas (US)
- University of North Texas Health Science Center (US)
- University of Pittsburgh (US)
- Washington University in St. Louis (US)
- Mallinckrodt (United States) (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103619
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00