Association between eGFR Trajectories and Cognitive Function in Midlife: Longitudinal Findings from the Bogalusa Heart Study

Our findings suggest that both high-steady downward and low-steady downward trend eGFR trajectories during adulthood are associated with worse global CF and cognition across all subdomains in midlife compared to the upward-to-downward trend trajectory. These results underscore the importance of maintaining stable renal function throughout adulthood to support cognitive health.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_100091
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between eGFR Trajectories and Cognitive Function in Midlife: Longitudinal Findings from the Bogalusa Heart Study

Flor Alvarado, Ileana De Anda‐Duran, Camilo Fernandez‐Alonso, Emily Wheeler Harville et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Association between eGFR Trajectories and Cognitive Function in Midlife: Longitudinal Findings from the Bogalusa Heart Study

Flor Alvarado, Ileana De Anda‐Duran, Camilo Fernandez‐Alonso, Emily Wheeler Harville, Eunsun Gill, XUANYI JIN, Soo Jung Kang, David J. Libon, Lydia A Bazzano
article en

Abstract

Our findings suggest that both high-steady downward and low-steady downward trend eGFR trajectories during adulthood are associated with worse global CF and cognition across all subdomains in midlife compared to the upward-to-downward trend trajectory. These results underscore the importance of maintaining stable renal function throughout adulthood to support cognitive health.

Alzheimer s & DementiaVol. 21(S3)
Tulane University (US), Rowan University (US)
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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