Polygenic Alzheimer's Disease Risk in Early‐ and Late‐Onset Alzheimer's Disease
These results suggest that LOAD genetic risk, aside from APOE4, is not a strong driver of EOAD age of onset; however, these variants may mediate some aspects of cognitive dysfunction in EOAD patients.
Authors
- K A Nudelman
- Kwangslk Nho
- Jackson Tr
- Thea Rosewood (ORCID: https://orcid.org/0000-0001-7025-0222)
- Julian V. Pentchev
- Marı́a C. Carrillo
- Liana G. Apostolova
- Tatiana M. Foroud
- Yen‐Ning Huang
- Andrew J. Saykin
- Ani Eloyan
- Jeffrey L. Dage
- Gil D. Rabinovici
- Brad C. Dickerson
Institutions
- Alzheimer's Association (US)
- University of Indianapolis (US)
- University of California, San Francisco (US)
- Brown University (US)
- Massachusetts General Hospital (US)
- University Memory and Aging Center (US)
- Indiana University Bloomington (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
- Indiana University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107414
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00