Balanced crystalloids versus normal saline for trauma resuscitation: A systematic review and meta-analysis
In trauma patients with TBI, NS was associated with lower mortality and more ventilator-free days than balanced crystalloids, whereas no significant difference was noted in trauma populations without TBI. Moreover, there was no significant difference between NS and balanced crystalloids in terms of AKI incidence, need for RRT, and ICU stay, suggesting that balanced crystalloids remain a safe and reasonable option for trauma resuscitation.
Authors
- Amira Shaban
- Mohamed Gafar Abdelrahim (ORCID: https://orcid.org/0000-0002-5522-6010)
- Hussam Elmelliti (ORCID: https://orcid.org/0000-0002-5394-3120)
- Wadah Musaed
- Ali Elkandow (ORCID: https://orcid.org/0000-0003-0949-7722)
- Hany A. Zaki
- Ahmed Shaban
- Eman E. Shaban
Institutions
- Mansoura University Hospital (EG)
- National Center for Cancer Care and Research (QA)
- Hamad Medical Corporation (QA)
Publication Details
- Journal
- The American Journal of Emergency Medicine
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1016/j.ajem.2025.12.030
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00