Examining the Connection Between Vascular Function and Cognitive Performance
Higher blood pressure and arterial stiffness were associated with worse verbal fluency, working memory, visuospatial, and executive function. Findings support, and add to prior work, such that vascular and cognitive assessments may differ by race, and a one-size-fits-all approach is not appropriate in delineating disease mechanisms and pathways. Future research should include diverse cohorts, most at risk for vascular disease and cognitive decline, to understand mechanisms, and ensure that diagnostics, treatments, and prevention strategies are appropriate and advantageous to all populations.
Authors
- Whitney Wharton
- Brian W. Kim (ORCID: https://orcid.org/0000-0001-6540-1110)
- Danielle D. Verble
- Brittany Butts (ORCID: https://orcid.org/0000-0002-4862-7086)
- Jordan Watson
- Chloe Park (ORCID: https://orcid.org/0000-0001-8302-7484)
- Hanfeng Huang (ORCID: https://orcid.org/0000-0003-2523-4439)
- Bruno L. Hammerschlag
- Enid Swatson
Institutions
- Harvard University (US)
- Emory University (US)
- Georgetown University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107028
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00