Examining the Connection Between Vascular Function and Cognitive Performance

Higher blood pressure and arterial stiffness were associated with worse verbal fluency, working memory, visuospatial, and executive function. Findings support, and add to prior work, such that vascular and cognitive assessments may differ by race, and a one-size-fits-all approach is not appropriate in delineating disease mechanisms and pathways. Future research should include diverse cohorts, most at risk for vascular disease and cognitive decline, to understand mechanisms, and ensure that diagnostics, treatments, and prevention strategies are appropriate and advantageous to all populations.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_107028
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Examining the Connection Between Vascular Function and Cognitive Performance

Whitney Wharton, Brian W. Kim, Danielle D. Verble, Brittany Butts et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Examining the Connection Between Vascular Function and Cognitive Performance

Whitney Wharton, Brian W. Kim, Danielle D. Verble, Brittany Butts, Jordan Watson, Chloe Park, Hanfeng Huang, Bruno L. Hammerschlag, Enid Swatson
article en

Abstract

Higher blood pressure and arterial stiffness were associated with worse verbal fluency, working memory, visuospatial, and executive function. Findings support, and add to prior work, such that vascular and cognitive assessments may differ by race, and a one-size-fits-all approach is not appropriate in delineating disease mechanisms and pathways. Future research should include diverse cohorts, most at risk for vascular disease and cognitive decline, to understand mechanisms, and ensure that diagnostics, treatments, and prevention strategies are appropriate and advantageous to all populations.

Alzheimer s & DementiaVol. 21(S1)
Harvard University (US), Emory University (US), Georgetown University (US), Massachusetts General Hospital (US)
Openalex Percentile: Top 34%
Dementia and Cognitive Impairment Research
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